Water contamination by drugs residues, with an emphasis in fluoxetine chloridrate

DOI: 10.15343/0104-7809.2012364556563

Authors

  • Sueli Ivone Borrely Doutora pelo Instituto de Pesquisas Energéticas e Nucleares. Tecnologista da Comissão Nacional de Energia Nuclear (CNEN). São Paulo- -SP, Brasil.
  • Suzete Maria L. Caminada Mestre pela UNICAMP – Departamento Saneamento Ambiental. Professora da Sociedade Educação e Cultura Ltda. Jaguariúna-SP, Brasil.
  • Alexandre Nunes Ponezi Doutor pela UNICAMP – Departamento Saneamento Ambiental. Pesquisador da Divisão de Microbiologia do Centro Pluridisciplinar de Pesquisas Químicas, Biológicas e Agrícolas (CPQBA) da UNICAMP. Campinas-SP, Brasil.
  • Dymes Rafael dos Santos Mestre pelo Instituto de Pesquisas Energéticas e Nucleares. Santos-SP, Brasil
  • Vanessa H. Ogihara Silva Engenheira Ambiental formada pela Universidade Estadual “Júlio de Mesquita Filho”. Mestranda do Programa de Pós-graduação em Tecnologia Nuclear do Instituto de Pesquisas Energéticas e Nucleares. São Paulo-SP, Brasil.

Keywords:

Water. Fluoxetine. Pharmaceutical Preparations.

Abstract

The objective of this paper was to review data on residues of medical products in aquatic environments and at wastewater
treatment plants. Secondarily the paper presents a discussion about the need for a good management of drugs residues and
effluents generated by this sector. Bringing the evidences of environmental possible damages reported by ecotoxicity data
on the effects of fluoxetine to Vibrio fischeri and H. azteca, aquatic organisms daily exposed to environmental contaminants.
From the results we observed that 0.3 mg.l-1 of fluoxetine hidrochloride induced lethality to H. azteca and 30 mg.l-
1 reduced the luminescence of Vibrio fischeri. This assay evidenced higher toxicity when we used the “generic” product.

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Published

2012-10-01

How to Cite

Borrely, S. I., L. Caminada, S. M. ., Nunes Ponezi, A., dos Santos, D. R. ., & H. Ogihara Silva, V. . (2012). Water contamination by drugs residues, with an emphasis in fluoxetine chloridrate: DOI: 10.15343/0104-7809.2012364556563. O Mundo Da Saúde, 36(4), 556–563. Retrieved from https://revistamundodasaude.emnuvens.com.br/mundodasaude/article/view/463

Issue

Vol. 36 No. 4 (2012): OCTOBER/DECEMBER 2012

Section

Articles