Calidad de vida en el trasplante de células madre hematopoyéticas en la pandemia de COVID-19: serie de casos
DOI:
https://doi.org/10.15343/0104-7809.202448e16112024PPalabras clave:
Calidad de vida, Trasplante de células madre hematopoyéticas, COVID-19, Cuidadores, Salud del adultoResumen
El trasplante de células madre hematopoyéticas es un tratamiento complejo con el objetivo de curar enfermedades malignas y benignas, que afecta directamente la calidad de vida de pacientes y cuidadores. Estudios previos a la pandemia han presentado aspectos de la carga del cuidador y la calidad de vida de ambos, y esta investigación contribuye a este vacío en el tema durante la pandemia. El objetivo fue evaluar y correlacionar la calidad de vida de los receptores de trasplantes de células madre hematopoyéticas con la calidad de vida y la carga de los cuidadores durante la pandemia de COVID-19. Se realizó una serie de casos con 16 días en un hospital público de Brasil, referente en América Latina. La calidad de vida de los pacientes trasplantados se evaluó mediante el Functional Assessment Cancer Therapy-Bone Marrow Transplantation, mientras que la calidad de vida de los cuidadores se evaluó mediante el Medical Outcomes Study 36-Item Short Form Health Survey, y la carga se evaluó mediante el Zarit Burden Interview. Hubo una menor percepción del bienestar funcional de los pacientes trasplantados y un peor estado general de salud de los cuidadores; la salud mental del cuidador interfirió en distintos dominios de la calidad de vida; hubo una correlación negativa entre la calidad de vida y la carga del cuidador. La pandemia ha tenido un impacto en la calidad de vida de las díadas; es necesario un apoyo adicional tanto para el paciente como para el cuidador.
Descargas
Citas
Oliveira C, et al. Transplante Alogênico de Células-Tronco Hematopoiéticas (TCTH) para tratamento de doença falciforme (Df): Estratégias e complicações distintas, mas resultados semelhantes com TCTH Haploidêntico (Haplo) e irmão HLA-Idêntico. Hematol Transfus Cell Ther [Internet]. 2021. [cited 2024 Jul 06]; 43:S302. Available from:: https://doi.org/10.1016/j.htct.2021.10.511.
Rasheed W, Niederwieser DW, Aljurf M. The HSCT Unit. In: Carreras, E., Dufour, C., Mohty, M., Kröger, N. (eds) The EBMT Handbook. Springer, Cham.[Internet]. 2019. [cited 2024 Jul 4]; p. 27–34. Available from: https://doi.org/10.1007/978-3-030-02278-54.
Machado, CAM, et al. Coping Religioso/Espiritual e Qualidade de Vida dos Sobreviventes de Câncer Cinco Anos após o Transplante de Células-Tronco Hematopoiéticas. Rev. Bras. Cancerol [Internet]. 2022[cited 2024 Jul 06]; 68(4):e-182812. Available from: https:// doi.org/10.32635/2176-9745.RBC.2022v68n4.2812
Rozwadowski M, et al. Promoting health and well-being through mobile health technology (Roadmap 2.0) in family caregivers and patients undergoing Hematopoietic Stem Cell Transplantation: Protocol for the development of a mobile randomized controlled trial. JMIR Res Protoc.[Internet]. 2020[cited 2024 Jul 06]; Sep 18;9(9):e19288. Available from: https://doi.org/10.2196/19288.
Posluszny DM, et al. Rates and predictors of nonadherence to the Post-Allogeneic Hematopoietic Cell Transplantation medical regimen in patients and caregivers. Transplant Cell Ther.[Internet]. 2022; [cited 2024 Jul 06]; Mar;28(3):165.e1-165.e9. Available from: https://doi.org/10.1016/j.jtct.2021.11.020
Pan Y-C, Lin Y-S. Systematic review and meta-analysis of prevalence of depression among caregivers of cancer patients. Front Psychiatry [Internet].2022[cited 2024 Jul 06]; 13: 817936. Available from: https://doi.org/10.3389/fpsyt.2022.817936
Oshiro NN, Nogueira LA, Santos YH, Guimarães PRB, Kalinke LP. Quality of life and financial toxicity of hematopoietic stem cell transplant recipients in COVID-19. Rev Lat Am Enfermagem [Internet]. 2023[cited 2024 Jul 06];31:e3996 . Available from: https://doi. org/10.1590%2F1518-8345.6688.3996
Murad MH, Sultan S, Haffar S, Bazerbachi F. Methodological quality and synthesis of case series and case reports. BMJ Evid Based Med [Internet]. 2018 Apr;23(2):60-63. Available from: https://doi.org/10.1136/bmjebm-2017-110853
Yildiz Kabak V, Atasavun Uysal S, Duger T. Screening supportive care needs, compliance with exercise program, quality of life, and anxiety level during the COVID-19 pandemic in individuals treated with hematopoietic stem cell transplantation. Support Care Cancer [Internet]. 2021[cited 2024 Jul 06]; Jul;29(7):4065–73. Available from: https://doi.org/10.1007/s00520-020-05965-1
McQuellon RP, et al. Quality of life measurement in bone marrow transplantation: development of the Functional Assessment of Cancer Therapy-Bone Marrow Transplant (FACT-BMT) scale. Bone Marrow Transplant [Internet]. 1997[cited 2024 Jul 06]; Feb;19(4):357–68. Available from: https://doi.org/10.1038/sj.bmt.1700672
Saris-Baglama RN, et al. QualityMetric health outcomesTM scoring software 4.0: installation guide. Lincoln Qual Inc. 2010.
Hébert R, Bravo G, Préville M. Reliability, Validity and Reference Values of the Zarit Burden Interview for Assessing Informal Caregivers of Community-Dwelling Older Persons with Dementia. Can J Aging [Internet]. 2000[cited 2024 Jul 06];19(4):494–507. Available from: https://psycnet.apa.org/doi/10.1017/S0714980800012484
King MT. The interpretation of scores from the EORTC quality of life questionnaire QLQ-C30. Qual Life Res [Internet]. 1996[cited 2024 Jul 06];5:555–67. Available from: https://doi.org/10.1007/bf00439229
Schober P, Boer C, Schwarte LA. Correlation coefficients: Appropriate use and interpretation. Anesth Analg [Internet]. 2018[cited 2024 Jul 06];126(5):1763–8. Available from: https://doi.org/10.1213/ane.0000000000002864
Amonoo HL, et al. Distress in a pandemic: Association of the coronavirus disease-2019 pandemic with distress and quality of life in hematopoietic stem cell transplantation. Transplant Cell Ther [Internet]. 2021[cited 2024 Jul 06]; Dec;27(12):1015.e1-1015.e7. Available from: https://doi.org/10.1016/j.jtct.2021.09.001
Chopra M, et al. Randomized controlled trial of Isha Kriya versus observation to improve quality of life in hematopoietic cell transplantation recipients. Transplant Cell Ther [Internet]. 2023[cited 2024 Jul 06];29(8):530.e1-530.e5. Available from: https://doi. org/10.1016/j.jtct.2023.05.010
Marques ACB, Szczepanik AP, Machado CAM, Santos PND, Guimarães PRB, Kalinke LP. Hematopoietic stem cell transplantation and quality of life during the first year of treatment. Rev Lat Am Enfermagem [Internet]. 2018[cited 2024 Jul 06]; 26: e3065. Available from: https://doi.org/10.1590/1518-8345.2474.3065
Knight JM, et al. Biobehavioral implications of Covid-19 for transplantation and cellular therapy recipients. Front Immunol [Internet]. 2022[cited 2024 Jul 06];13: 877558. Available from: https://doi.org/10.3389/fimmu.2022.877558
Amonoo HL, et al. Sharing and caring: The impact of social support on quality of life and health outcomes in hematopoietic stem cell transplantation. Cancer [Internet]. 2021[cited 2024 Jul 06];127(8):1260–5. Available from: https://doi.org/10.1002/cncr.33455
Yang G, Zhang H, Yang Y. Challenges and countermeasures of integrative cancer therapy in the epidemic of COVID-19. Integr Cancer Ther [Internet]. 2020[cited 2024 Jul 06]; Available from: https://doi.org/10.1177/1534735420912811
Lyon D. COVID-19, Cancer, and Financial Toxicity. Oncol Nurs Forum [Internet].2020[cited 2024 Jul 06]; 47(3):253-4. Available from: https://doi.org/10.1188/20.onf.253-254
Tan K, Fredrickson B, Santos H, Wood W, Schwartz T, Mayer D. Psychological processing among caregivers of allogeneic bone marrow transplant recipients: Qualitative findings from a longitudinal study. J Psychosoc Oncol [Internet]. 2023[cited 2024 Jul 06]; May 4;41(3):321–36. Available from: https://doi.org/10.1080/07347332.2022.2107467
Monteiro JKMF, Sá SPC, Bezerra DRC, Borges WD. Recomendações aos cuidadores e familiares de idosos mediante o COVID-19. Res Soc Dev [Internet]. 2020[cited 2024 Jul 06];9(11):e4039119798. Available from: http://dx.doi.org/10.33448/rsd-v9i11.9798
Winterling J, Kisch A, Alvariza A, Årestedt K, Bergkvist K. Preparedness for family caregiving prior to allogeneic hematopoietic stem cell transplantation. Palliat Support Care [Internet]. 2022[cited 2024 Jul 06];20(4):519–26. Available from: https://doi.org/10.1017/ s1478951521001346
Kisch AM, Bergkvist K, Alvariza A, Årestedt K, Winterling J. Family caregivers’ support needs during allo-HSCT—a longitudinal study. Support Care Cancer [Internet]. 2021[cited 2024 Jul 06];29(6):3347–56. Available from: https://doi.org/10.1007%2 Fs00520-020-05853-8
Descargas
Publicado
Cómo citar
Número
Sección
Licencia
Derechos de autor 2024 O Mundo da Saúde
Esta obra está bajo una licencia internacional Creative Commons Atribución 4.0.
