Duração de sintomas por COVID-19 em pacientes pós-internamento em hospitais terciários no Ceará
10.15343/0104-7809.202246422433P
Palabras clave:
Doença por vírus COVID-19. Coronavírus. Avaliação de sintomas. Rastreamento.Resumen
Apesar do avanço no conhecimento sobre COVID-19, pouco ainda se sabe sobre o percurso da doença e seus desfechos a longo prazo. Assim, surge a investigação pós pandemia centrada nas sequelas e complicações causadas pelo Coronavírus. Desse modo, objetivou-se investigar vestígios sintomatológicos e tempo de duração em pacientes pós internamento por COVID-19 advindos de três hospitais regionais cearenses. Trata-se de um estudo descritivo, analítico do tipo transversal com abordagem quantitativa realizado no período de agosto a outubro de 2021 por meio da telepesquisa. A amostra final foi constituída de 49 pacientes na primeira onda e 153 na segunda, totalizando 202 participantes. Os dados foram tabulados em planilha eletrônica Excel® e analisados conforme estatística descritiva. Apresenta-se uma prevalência de pacientes do sexo masculino, 31 (63,3%) no primeiro período investigado, e 86 (56,2%) no segundo período. Na investigação de sintomas físicos destacou-se fadiga/cansaço, apresentando 23 (46,9%) e 69 (45,1%) conforme onda, seguido de inapetência 13 (26,5%) e (40,5%). Falta de ar teve destaque na segunda onda com 39 (25,5%). Sintomas como perda de memória, tosse e dor no peito aparecem como sendo os mais duradouros, sendo prevalentes por até 4 meses após a alta hospitalar. Enquanto na 2ª onda dor no peito é citada com duração de até 6 meses. Neste contexto, este estudo expõe os principais sintomas relatados, apontando para a necessidade iminente de estratégias públicas de serviços de acompanhamento e intervenção junto a estes pacientes.
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United States During the First 10 Weeks of the Pandemic. Front Sociol. 2020; 5(47):1-10. https://doi.org/10.3389/fsoc.2020.00047
2. Organização Mundial da Saúde. Coronavirus disease (COVID-19) Situation Report – 193. 2019; acesso 2022 de fev de 17. https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200731-COVID-19-sitrep-193.pdf?sfvrsn=42a0221d_4
3. Michelen M, Cheng V, Manoharan L, Elkheir N, Dagens D, Hastie C et al. What are the long-term symptoms and complications of COVID-19: a protocol for a living systematic review. F1000Research. 2020; 9(1455):1-13. https://doi.org/10.12688/f1000research.27284.2
4. Fiani B, Covarrubias C, Desai A, Sekhon M, Jarrah R. A Contemporary Review of Neurological Sequelae of COVID-19. Front. Neurol. 2020;11:640. https://doi.org/10.3389/fneur.2020.00640
5. Lang M , Buch MD, Li WA, Mehan AL, Lang TM. Leslie-Mazwi SP. Rincon. Leukoencephalopathy Associated with Severe COVID-19 Infection: Sequela of Hypoxemia? Am J. Neurol. 2020;41(9):1641-1645. https://doi.org/10.3174/ajnr.A6671
6. Gavriatopoulou M, Ntanasis-Stathopoulos I, Korompoki E, et al. Emerging treatment strategies for COVID 19 infection. Clin Exp Med. 2021;21:167–179. https://doi.org/10.1007/s10238-020-00671-y
7. Gil AC. Métodos e técnicas de pesquisa social. 5ª ed. São Paulo, Atlas, 1999.
8. Corey CR, Freeman HE. Use of telephone interviewing in health care research. Health Serv Res. 1990; Acesso em 04 ago. 2021; 25:129-44. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1065612/
9. Marcus AC, Crane AL. Telephone surveys in public health research. Med Care. 1986; Acesso em 06 ago. 2021 ;24:97-112. Available from: https://www.jstor.org/stable/3764591
10. Baig AM. Deleterious Outcomes in Long-Hauler COVID-19: The Effects of SARS-CoV-2 on the CNS in Chronic COVID Syndrome. ACS Chem Neurosci. 2020;11(24):4017-4020. https://doi.org/10.1021/acschemneuro.0c00725
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12. Mauvais-Jarvis, F. Aging, male sex, obesity, and metabolic inflammation create the perfect storm for COVID-19. Diabetes. 2020;69(9):1857-1863. https://doi.org/10.2337/dbi19-0023
13. Desiderio VL, Fabio V, Cárnio EC, Godoy S, Silva HB, Marchi-Alves LM. Variáveis associadas ao desfecho clínico de pacientes hospitalizados por COVID-19. Rev Med USP. 2021; 100(5):431-441. https://doi.org/10.11606/issn.1679-9836.v100i5p431-441
14. Daniel CR, Baroni MP, Ruaro JA, Fréz AR. Are we looking at post-COVID patients as we should. J Physiother Res. 2020;10(4):588-590. http://dx.doi.org/10.17267/2238-2704rpf.v10i4.3238
15. Castro APCR, Santos Nascimento J, Palladini MC, Pelloso LRCA, Barbosa MHL. Dor no Paciente com Síndrome Pós-COVID-19. Rev Cient HSI. 2021; 5(2): 56-62. https://www.hospitalsantaizabel.org.br/conteudo/rev/001/arq/pdf/000027.pdf
16. Santana AV, Fontana AD, Pitta F. Pulmonary rehabilitation after COVID-19. J Bras Pneum. 2021; 47(1):1-3. https://doi.org/10.36416/1806-3756/e20210034
17. Garrigues E, Janvier P, Kherabi Y, et al. Post-discharge persistent symptoms and health-related quality of life after hospitalization for COVID-19. J Infect. 2020;81(6):e4-e6. https://doi.org/10.1016/j.jinf.2020.08.029
18. Xiong Q, Xu M, Li J. Clinical sequelae of COVID-19 survivors in Wuhan, China: a single-centre longitudinal study. Clin Microbiol Infection, 2020;27(1):89-95. https://doi.org/10.1016/j.cmi.2020.09.023
19. Lee AM, Wong JG, McAlonan GM, Cheung V, Cheung C, Sham PC, Chu CM, Wong PC, Tsang KW, Chua SE. Stress and psychological distress among SARS survivors 1 year after the outbreak. Can J Psychiatry. 2007.;52(4):233-40. https://doi.org/10.1177%2F070674370705200405
20. Schneider VM, Luna JM, Hoffmann HH, Sánchez-Rivera FJ, Leal AA, Ashbrook AW, et al. Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks. Elsevier Inc. 2020;184(1):120-132. https://doi.org/10.1016/j.cell.2020.12.006
21. Kaseda ET, Levine AJ. Post-traumatic stress disorder: A differential diagnostic consideration for COVID-19 survivors. Clin Neuropsychol. 2020;34(7-8):1498-1514. https://doi.org/10.1080/13854046.2020.1811894
22. Carvalho-Schneider C, Laurent E, Lemaignen A, Beaufils E, Bourbao-Tournois C, Laribi S, Flament T, et al. Follow-up of adults with noncritical COVID-19 two months after symptom onset. Clin Microbiol Infect. 2021; 27(2):258-263. https://doi.org/10.1016/j.cmi.2020.09.052
23. Wu Q, Zhou L, Sun X, Yan Z, Hu C, Wu J. et al. Altered Lipid Metabolism in recovered SARS Patients Twelve Years after Infection. Sci Rep. 2017;22;7(1):9110. https://doi.org/10.1038/s41598-017-09536-z
24. Zacharias H, Shirish D, Koduri G, D'Cruz D. Rheumatological complications of COVID 19. Aut Reviews. 2021;20(9):1-9. https://doi.org/10.1016/j.autrev.2021.102883
25. Korompoki E, Gavriatopoulou M, Hicklen RS, Ntanasis-Stathopoulos I, Kastritis E, Fotiou D, et al. Epidemiology and organ specific sequelae of post-acute COVID19: A narrative review. J Inf. 2021;83(1):1-16. https://doi.org/10.1016/j.jinf.2021.05.004
26. Visco V, Vitale C, Rispoli A, Izzo C, Virtuoso N, Ferruzzi GJ, et al. Post-COVID-19 Syndrome: Involvement and Interactions between Respiratory, Cardiovascular and Nervous Systems. J Clin Med. 2022;11(3):524. https://doi.org/10.3390/jcm11030524
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2022-11-04
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Ribeiro de Castro Júnior, A., Freire Gomes, T., Socorro Martins, M. I., de Paula Santos, M. A., Paiva de Abreu, L. D., Aragão de Paiva, I., & Franco Moreira, F. J. (2022). Duração de sintomas por COVID-19 em pacientes pós-internamento em hospitais terciários no Ceará: 10.15343/0104-7809.202246422433P. O Mundo Da Saúde, 46, 422–433. Recuperado a partir de https://revistamundodasaude.emnuvens.com.br/mundodasaude/article/view/1438
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