Influence of exposure to cigarette smoke and physical training in appetite and body development in rats

DOI: 10.15343/0104-7809.20164002169179

Abstract

The tobacco has the potential to cause changes in the hormonal system, appetite and therefore food intake. In turn,
physical training increases metabolic demand, exerts a substantial effect on the energy balance. This study aimed to
verify the influence of smoking and physical training in appetite and the development of body weight in rats. Rats Wistar
were used (n=40, between 200g and 250g) rats were distributed into four groups: control (C); Trained control (TC);
Exposure (E); Trained / exposure (TE). Exposure to cigarette smoke (ECS) and training (swimming) lasted 15 weeks.
The animals were weighed weekly and food intake weighed daily. Analyzed with two-way ANOVA and was adopted
a significance level of 5%. The ECS intake in rats was lower compared to the non ECS (p=0.001). The trained rats
had lower values in intake compared to untrained (p=0.044). The statistical interaction between factors (smoking and
swimming) interfered with the intake (p=0.013). The growth curves showed lower body weight in the groups ECS. Was
no statistical interaction between smoking and factors swimming to body weight (p=0.046). Statistical difference with
higher values for the weights of the heart, lung, and tibia in group no ECS, compared to rats ECS. We conclude that ECS
inhibits appetite and promotes loss in body development. And, physical training has chronically negative influence on
energy balance, with reduction in weight gain. However, it does not interfere with body development, and beneficial
unlike exposure to cigarette smoke.