Duration of symptoms caused by COVID-19 in patients discharged from tertiary hospitals in Ceará
10.15343/0104-7809.202246422433I
Keywords:
COVID-19 virus disease. Coronavirus. Symptom assessment. Tracking.Abstract
Despite advances in knowledge about COVID-19, little is known about the course of the disease and its long-term outcomes. Therefore, post-pandemic research has focused on the sequelae and complications caused by the Coronavirus. Thus, the objective was to investigate symptomatological remains and their duration of discharged patients hospitalized for COVID-19 from three regional hospitals in Ceará. This is a descriptive, analytical cross-sectional study with a quantitative approach carried out from August to October 2021 through telesurvey. The final sample consisted of 49 patients in the first wave of the pandemic and 153 in the second, totaling 202 participants. Data were tabulated in an Excel® spreadsheet and analyzed according to descriptive statistics. There is a prevalence of male patients, 31 (63.3%) in the first period investigated, and 86 (56.2%) in the second wave. In the investigation of physical symptoms, fatigue/tiredness stood out, identified in 23 (46.9%) and 69 (45.1%) individuals according to the wave, followed by a lack of appetite in 13 (26.5%) and (40.5%). Shortness of breath was highlighted in the second period among 39 (25.5%) individuals. Symptoms such as memory loss, cough, and chest pain appear to be the most lasting, and were prevalent for up to 4 months after hospital discharge. While in the 2nd wave chest pain was cited lasting up to 6 months. In this context, this study exposes the main symptoms reported, pointing to the imminent need for public strategies for monitoring and intervention services with these patients.
Downloads
Download data is not yet available.
References
1. Finch WH, Hernández Finch ME. Poverty and COVID-19: Rates of Incidence and Deaths in the
United States During the First 10 Weeks of the Pandemic. Front Sociol. 2020; 5(47):1-10. https://doi.org/10.3389/fsoc.2020.00047
2. Organização Mundial da Saúde. Coronavirus disease (COVID-19) Situation Report – 193. 2019; acesso 2022 de fev de 17. https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200731-COVID-19-sitrep-193.pdf?sfvrsn=42a0221d_4
3. Michelen M, Cheng V, Manoharan L, Elkheir N, Dagens D, Hastie C et al. What are the long-term symptoms and complications of COVID-19: a protocol for a living systematic review. F1000Research. 2020; 9(1455):1-13. https://doi.org/10.12688/f1000research.27284.2
4. Fiani B, Covarrubias C, Desai A, Sekhon M, Jarrah R. A Contemporary Review of Neurological Sequelae of COVID-19. Front. Neurol. 2020;11:640. https://doi.org/10.3389/fneur.2020.00640
5. Lang M , Buch MD, Li WA, Mehan AL, Lang TM. Leslie-Mazwi SP. Rincon. Leukoencephalopathy Associated with Severe COVID-19 Infection: Sequela of Hypoxemia? Am J. Neurol. 2020;41(9):1641-1645. https://doi.org/10.3174/ajnr.A6671
6. Gavriatopoulou M, Ntanasis-Stathopoulos I, Korompoki E, et al. Emerging treatment strategies for COVID 19 infection. Clin Exp Med. 2021;21:167–179. https://doi.org/10.1007/s10238-020-00671-y
7. Gil AC. Métodos e técnicas de pesquisa social. 5ª ed. São Paulo, Atlas, 1999.
8. Corey CR, Freeman HE. Use of telephone interviewing in health care research. Health Serv Res. 1990; Acesso em 04 ago. 2021; 25:129-44. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1065612/
9. Marcus AC, Crane AL. Telephone surveys in public health research. Med Care. 1986; Acesso em 06 ago. 2021 ;24:97-112. Available from: https://www.jstor.org/stable/3764591
10. Baig AM. Deleterious Outcomes in Long-Hauler COVID-19: The Effects of SARS-CoV-2 on the CNS in Chronic COVID Syndrome. ACS Chem Neurosci. 2020;11(24):4017-4020. https://doi.org/10.1021/acschemneuro.0c00725
11. Almeida França NM, Pinheiro GS, Barbosa LAO, Avena KM. Síndrome respiratória aguda grave por COVID‐19: perfil clínico e epidemiológico dos pacientes internados em unidades de terapia intensiva no Brasil. Braz J Infect Dis. 2021;25: 101147. https://doi.org/10.1016/j.bjid.2020.101147
12. Mauvais-Jarvis, F. Aging, male sex, obesity, and metabolic inflammation create the perfect storm for COVID-19. Diabetes. 2020;69(9):1857-1863. https://doi.org/10.2337/dbi19-0023
13. Desiderio VL, Fabio V, Cárnio EC, Godoy S, Silva HB, Marchi-Alves LM. Variáveis associadas ao desfecho clínico de pacientes hospitalizados por COVID-19. Rev Med USP. 2021; 100(5):431-441. https://doi.org/10.11606/issn.1679-9836.v100i5p431-441
14. Daniel CR, Baroni MP, Ruaro JA, Fréz AR. Are we looking at post-COVID patients as we should. J Physiother Res. 2020;10(4):588-590. http://dx.doi.org/10.17267/2238-2704rpf.v10i4.3238
15. Castro APCR, Santos Nascimento J, Palladini MC, Pelloso LRCA, Barbosa MHL. Dor no Paciente com Síndrome Pós-COVID-19. Rev Cient HSI. 2021; 5(2): 56-62. https://www.hospitalsantaizabel.org.br/conteudo/rev/001/arq/pdf/000027.pdf
16. Santana AV, Fontana AD, Pitta F. Pulmonary rehabilitation after COVID-19. J Bras Pneum. 2021; 47(1):1-3. https://doi.org/10.36416/1806-3756/e20210034
17. Garrigues E, Janvier P, Kherabi Y, et al. Post-discharge persistent symptoms and health-related quality of life after hospitalization for COVID-19. J Infect. 2020;81(6):e4-e6. https://doi.org/10.1016/j.jinf.2020.08.029
18. Xiong Q, Xu M, Li J. Clinical sequelae of COVID-19 survivors in Wuhan, China: a single-centre longitudinal study. Clin Microbiol Infection, 2020;27(1):89-95. https://doi.org/10.1016/j.cmi.2020.09.023
19. Lee AM, Wong JG, McAlonan GM, Cheung V, Cheung C, Sham PC, Chu CM, Wong PC, Tsang KW, Chua SE. Stress and psychological distress among SARS survivors 1 year after the outbreak. Can J Psychiatry. 2007.;52(4):233-40. https://doi.org/10.1177%2F070674370705200405
20. Schneider VM, Luna JM, Hoffmann HH, Sánchez-Rivera FJ, Leal AA, Ashbrook AW, et al. Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks. Elsevier Inc. 2020;184(1):120-132. https://doi.org/10.1016/j.cell.2020.12.006
21. Kaseda ET, Levine AJ. Post-traumatic stress disorder: A differential diagnostic consideration for COVID-19 survivors. Clin Neuropsychol. 2020;34(7-8):1498-1514. https://doi.org/10.1080/13854046.2020.1811894
22. Carvalho-Schneider C, Laurent E, Lemaignen A, Beaufils E, Bourbao-Tournois C, Laribi S, Flament T, et al. Follow-up of adults with noncritical COVID-19 two months after symptom onset. Clin Microbiol Infect. 2021; 27(2):258-263. https://doi.org/10.1016/j.cmi.2020.09.052
23. Wu Q, Zhou L, Sun X, Yan Z, Hu C, Wu J. et al. Altered Lipid Metabolism in recovered SARS Patients Twelve Years after Infection. Sci Rep. 2017;22;7(1):9110. https://doi.org/10.1038/s41598-017-09536-z
24. Zacharias H, Shirish D, Koduri G, D'Cruz D. Rheumatological complications of COVID 19. Aut Reviews. 2021;20(9):1-9. https://doi.org/10.1016/j.autrev.2021.102883
25. Korompoki E, Gavriatopoulou M, Hicklen RS, Ntanasis-Stathopoulos I, Kastritis E, Fotiou D, et al. Epidemiology and organ specific sequelae of post-acute COVID19: A narrative review. J Inf. 2021;83(1):1-16. https://doi.org/10.1016/j.jinf.2021.05.004
26. Visco V, Vitale C, Rispoli A, Izzo C, Virtuoso N, Ferruzzi GJ, et al. Post-COVID-19 Syndrome: Involvement and Interactions between Respiratory, Cardiovascular and Nervous Systems. J Clin Med. 2022;11(3):524. https://doi.org/10.3390/jcm11030524
United States During the First 10 Weeks of the Pandemic. Front Sociol. 2020; 5(47):1-10. https://doi.org/10.3389/fsoc.2020.00047
2. Organização Mundial da Saúde. Coronavirus disease (COVID-19) Situation Report – 193. 2019; acesso 2022 de fev de 17. https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200731-COVID-19-sitrep-193.pdf?sfvrsn=42a0221d_4
3. Michelen M, Cheng V, Manoharan L, Elkheir N, Dagens D, Hastie C et al. What are the long-term symptoms and complications of COVID-19: a protocol for a living systematic review. F1000Research. 2020; 9(1455):1-13. https://doi.org/10.12688/f1000research.27284.2
4. Fiani B, Covarrubias C, Desai A, Sekhon M, Jarrah R. A Contemporary Review of Neurological Sequelae of COVID-19. Front. Neurol. 2020;11:640. https://doi.org/10.3389/fneur.2020.00640
5. Lang M , Buch MD, Li WA, Mehan AL, Lang TM. Leslie-Mazwi SP. Rincon. Leukoencephalopathy Associated with Severe COVID-19 Infection: Sequela of Hypoxemia? Am J. Neurol. 2020;41(9):1641-1645. https://doi.org/10.3174/ajnr.A6671
6. Gavriatopoulou M, Ntanasis-Stathopoulos I, Korompoki E, et al. Emerging treatment strategies for COVID 19 infection. Clin Exp Med. 2021;21:167–179. https://doi.org/10.1007/s10238-020-00671-y
7. Gil AC. Métodos e técnicas de pesquisa social. 5ª ed. São Paulo, Atlas, 1999.
8. Corey CR, Freeman HE. Use of telephone interviewing in health care research. Health Serv Res. 1990; Acesso em 04 ago. 2021; 25:129-44. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1065612/
9. Marcus AC, Crane AL. Telephone surveys in public health research. Med Care. 1986; Acesso em 06 ago. 2021 ;24:97-112. Available from: https://www.jstor.org/stable/3764591
10. Baig AM. Deleterious Outcomes in Long-Hauler COVID-19: The Effects of SARS-CoV-2 on the CNS in Chronic COVID Syndrome. ACS Chem Neurosci. 2020;11(24):4017-4020. https://doi.org/10.1021/acschemneuro.0c00725
11. Almeida França NM, Pinheiro GS, Barbosa LAO, Avena KM. Síndrome respiratória aguda grave por COVID‐19: perfil clínico e epidemiológico dos pacientes internados em unidades de terapia intensiva no Brasil. Braz J Infect Dis. 2021;25: 101147. https://doi.org/10.1016/j.bjid.2020.101147
12. Mauvais-Jarvis, F. Aging, male sex, obesity, and metabolic inflammation create the perfect storm for COVID-19. Diabetes. 2020;69(9):1857-1863. https://doi.org/10.2337/dbi19-0023
13. Desiderio VL, Fabio V, Cárnio EC, Godoy S, Silva HB, Marchi-Alves LM. Variáveis associadas ao desfecho clínico de pacientes hospitalizados por COVID-19. Rev Med USP. 2021; 100(5):431-441. https://doi.org/10.11606/issn.1679-9836.v100i5p431-441
14. Daniel CR, Baroni MP, Ruaro JA, Fréz AR. Are we looking at post-COVID patients as we should. J Physiother Res. 2020;10(4):588-590. http://dx.doi.org/10.17267/2238-2704rpf.v10i4.3238
15. Castro APCR, Santos Nascimento J, Palladini MC, Pelloso LRCA, Barbosa MHL. Dor no Paciente com Síndrome Pós-COVID-19. Rev Cient HSI. 2021; 5(2): 56-62. https://www.hospitalsantaizabel.org.br/conteudo/rev/001/arq/pdf/000027.pdf
16. Santana AV, Fontana AD, Pitta F. Pulmonary rehabilitation after COVID-19. J Bras Pneum. 2021; 47(1):1-3. https://doi.org/10.36416/1806-3756/e20210034
17. Garrigues E, Janvier P, Kherabi Y, et al. Post-discharge persistent symptoms and health-related quality of life after hospitalization for COVID-19. J Infect. 2020;81(6):e4-e6. https://doi.org/10.1016/j.jinf.2020.08.029
18. Xiong Q, Xu M, Li J. Clinical sequelae of COVID-19 survivors in Wuhan, China: a single-centre longitudinal study. Clin Microbiol Infection, 2020;27(1):89-95. https://doi.org/10.1016/j.cmi.2020.09.023
19. Lee AM, Wong JG, McAlonan GM, Cheung V, Cheung C, Sham PC, Chu CM, Wong PC, Tsang KW, Chua SE. Stress and psychological distress among SARS survivors 1 year after the outbreak. Can J Psychiatry. 2007.;52(4):233-40. https://doi.org/10.1177%2F070674370705200405
20. Schneider VM, Luna JM, Hoffmann HH, Sánchez-Rivera FJ, Leal AA, Ashbrook AW, et al. Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks. Elsevier Inc. 2020;184(1):120-132. https://doi.org/10.1016/j.cell.2020.12.006
21. Kaseda ET, Levine AJ. Post-traumatic stress disorder: A differential diagnostic consideration for COVID-19 survivors. Clin Neuropsychol. 2020;34(7-8):1498-1514. https://doi.org/10.1080/13854046.2020.1811894
22. Carvalho-Schneider C, Laurent E, Lemaignen A, Beaufils E, Bourbao-Tournois C, Laribi S, Flament T, et al. Follow-up of adults with noncritical COVID-19 two months after symptom onset. Clin Microbiol Infect. 2021; 27(2):258-263. https://doi.org/10.1016/j.cmi.2020.09.052
23. Wu Q, Zhou L, Sun X, Yan Z, Hu C, Wu J. et al. Altered Lipid Metabolism in recovered SARS Patients Twelve Years after Infection. Sci Rep. 2017;22;7(1):9110. https://doi.org/10.1038/s41598-017-09536-z
24. Zacharias H, Shirish D, Koduri G, D'Cruz D. Rheumatological complications of COVID 19. Aut Reviews. 2021;20(9):1-9. https://doi.org/10.1016/j.autrev.2021.102883
25. Korompoki E, Gavriatopoulou M, Hicklen RS, Ntanasis-Stathopoulos I, Kastritis E, Fotiou D, et al. Epidemiology and organ specific sequelae of post-acute COVID19: A narrative review. J Inf. 2021;83(1):1-16. https://doi.org/10.1016/j.jinf.2021.05.004
26. Visco V, Vitale C, Rispoli A, Izzo C, Virtuoso N, Ferruzzi GJ, et al. Post-COVID-19 Syndrome: Involvement and Interactions between Respiratory, Cardiovascular and Nervous Systems. J Clin Med. 2022;11(3):524. https://doi.org/10.3390/jcm11030524
Downloads
Published
2022-11-04
How to Cite
Ribeiro de Castro Júnior, A., Freire Gomes, T., Socorro Martins, M. I., de Paula Santos, M. A., Paiva de Abreu, L. D., Aragão de Paiva, I., & Franco Moreira, F. J. (2022). Duration of symptoms caused by COVID-19 in patients discharged from tertiary hospitals in Ceará: 10.15343/0104-7809.202246422433I. O Mundo Da Saúde, 46, 422–433. Retrieved from https://revistamundodasaude.emnuvens.com.br/mundodasaude/article/view/1438
Issue
Section
Articles
