Trend analysis of new hepatitis C cases in Brazil: 2011 to 2019
DOI:
https://doi.org/10.15343/0104-7809.202448e16212024PKeywords:
Hepatitis C, Epidemiology, Communicable Disease ControlAbstract
Hepatitis C virus (HCV) infection is a disease transmitted through exposure to the blood or other body fluids of infected people as a result of unsafe health practices and care, unscreened blood transfusions, injecting drug use, and sexual practices without the use of condoms. This study aims to analyse the trend in new cases of hepatitis C in Brazil from 2011 to 2019. Data were collected from HCV cases registered in the Notifiable Diseases Information System in all regions of Brazil from 2011 to 2019. The information collected included the following variables: sex, colour/race, region of notification, transmission mechanism and age group. A trend analysis was then performed using the Joinpoint programme with a 5% significance level. In Brazil, 154,978 new cases of hepatitis C were reported. Regarding the trend of new hepatitis C cases in Brazil between 2011 and 2019, a decreasing trend was observed between 2016 and 2019. The data analysed in the study showed that new cases of hepatitis C in Brazil are on a downward trend, especially among men, whites, children under one year of age, people aged 20-59 years, and in the southern and central-western regions of the country. Despite being a notifiable disease, several variables remain blank, highlighting the low quality of information collection. Brazil faces significant barriers to eradicating the disease by 2030. Overcoming these barriers will require investment in infrastructure and comprehensive public policies, as well as an integrated approach that regional the various variables involved.
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References
World Health Organization (WHO). Global Hepatitis Report 2024. 2024. https://www.who.int/publications/i/item/9789240091672
Roudot-Thoraval F. Epidemiology of hepatitis C virus infection. Clin Res Hepatol Gastroenterol. 2021;45(3):101596. doi:10.1016/j. clinre.2020.101596.
Brasil. Ministério da Saúde. Departamento de Doenças de Condições Crônicas e Infecções Sexualmente Transmissíveis. Plano para Eliminação da Hepatite C no Brasil. 2018. https://www.gov.br/aids/pt-br/central-de-conteudo/publicacoes/2019/plano-para eliminacao-da-hepatite-c-no-brasil/view. Acessado em: 11 de outubro de 2024.
Castro LMAM de, Sousa GC de. Estudo epidemiológico da prevalência e letalidade dos casos de hepatite C ocorridas no Brasil: 2010- 2019. REASE [Internet]. 28º de fevereiro de 2023 [citado 11º de outubro de 2024];9(2):1018-26. Disponível em: https://periodicorease. pro.br/rease/article/view/8602
de Brito RJVC, da Silva LF, Santos MB, de Moura PMMF, de Souza CDF, do Carmo RF. A time series analysis of detection and mortality of hepatitis C in Brazil, 2008-2018. BMC Infect Dis. 2022 Jan 24;22(1):81. doi: 10.1186/s12879-022-07063-5. PMID: 35073878; PMCID: PMC8785020.
Kim HJ, Fay MP, Feuer EJ, Midthune DN. Permutation tests for joinpoint regression with applications to cancer rates. Stat Med. 2000 Feb 15;19(3):335-51. doi: 10.1002/(sici)1097-0258(20000215)19:33.0.co;2-z. Erratum in: Stat Med 2001 Feb 28;20(4):655. PMID: 10649300.
U. S. National Cancer Institute. Joinpoint help system: number of joinpoints; 2022. https://surveillance.cancer.gov/help/joinpoint/ setting-parameters/method-and-parameters-tab/number-of-joinpoints. Acessado em: 09 de Outubro de 2024.
U. S. National Cancer Institute. Joinpoint help system: number of joinpoints; 2022. https://surveillance.cancer.gov/help/joinpoint/ tech-help/frequently-asked-questions/linear-or-log-linear-model. Acessado em: 09 de Outubro de 2024.
Kim HJ, Luo J, Chen HS, Green D, Buckman D, Byrne J, Feuer EJ. Improved confidence interval for average annual percent change in trend analysis. Stat Med. 2017 Aug 30;36(19):3059-3074. doi: 10.1002/sim.7344. Epub 2017 Jun 5. PMID: 28585245; PMCID: PMC5652079.
Report of National Cancer Registry Programme (ICMR-NCDIR), Bengaluru, India 2020.
National Cancer Institute (NCI). Joinpoint Regression Program, Version 5.0.2. - Statistical Methodology and Applications Branch, Surveillance Research Program. 2023. https://surveillance.cancer.gov/joinpoint/.
Hanus JS, Ceretta LB, Simões PW, Uuon L. Incidência de hepatite C no Brasil. Rev Soc Bras Med Trop. 2015;48:665–73.
Wolff FH, Fuchs SC, Barcellos NN, de Alencastro PR, Ikeda ML, Brandão AB, et al. Co-infecção pelo vírus da hepatite C em pacientes infectados pelo HIV no sul do Brasil: distribuição de genótipos e correlatos clínicos. PLoS ONE. 2010;5(5):e10494.
Benzaken AS, Girade R, Catapan E, Pereira GFM, Almeida EC, Vivaldini S, et al. Carga da doença da hepatite C e estratégias para eliminação até 2030 no Brasil. Uma abordagem de modelagem matemática. Braz J Infect Dis. 2019;23(3):182–90.
Jin F, Dore GJ, Matthews G, Luhmann N, Macdonald V, Bagis S, et al. Prevalence and incidence of hepatitis C virus infection in men who have sex with men: a systematic review and meta-analysis. Lancet Gastroenterol Hepatol. 2021;6(1):39-56. doi:10.1016/ S2468-1253(20)30303-4
Behzadifar M, Behzadifar M, Bragazzi NL. A systematic review and meta-analysis of the prevalence of hepatitis C virus infection in people who inject drugs in Iran. BMC Public Health. 2020;20(1):62. Published 2020 Jan 14. doi:10.1186/s12889-020-8175-1
Coppola N, Alessio L, Onorato L, Sagnelli C, Macera M, Sagnelli E, et al. Epidemiology and management of hepatitis C virus infections in immigrant populations. Infect Dis Poverty. 2019;8(1):17. Publicado em 15 de Março de 2019. doi:10.1186/s40249-019- 0528-6
Monte CF do, Nascimento LC do, Brito KPSS de, Batista AS de L, Ferreira JS, Campos L da S, Andrade TJFD, Ferreira AF. Idosos frente a infecções sexualmente transmissíveis: uma revisão integrativa. Braz. J. Hea. Rev. [Internet]. 2021 Maio 17 [citado em 13 out. 2024];4(3):10804-1. Available from: https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/29883
Borges JML, Oku RMG, Muniz SM de A, Belotto DL de C, Cartaxo HB. Sífilis e hepatites na população idosa: perfil epidemiológico, distribuição geográfica e tendências na região nordeste do Brasil. Braz. J. Hea. Rev. [Internet]. 2024 Mar. 13 [citado em 13 out. 2024];7(2):e68059. Disponível: https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/68059
Aghaei AM, Gholami J, Sangchooli A, Rostam-Abadi Y, Olamazadeh S, Ardeshir M, et al. Prevalence of injecting drug use and HIV, hepatitis B, and hepatitis C in people who inject drugs in the Eastern Mediterranean region: a systematic review and meta-analysis. Lancet Glob Health. 2023;11(8):e1225-e1237. doi:10.1016/S2214-109X(23)00267-X
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