Dietary intake and cardiovascular risk in children and adolescents after cancer treatment
DOI:
https://doi.org/10.15343/0104-7809.202448e15452023PKeywords:
Nutritional Status, Anthropometry, Obesity, Children, TeenagersAbstract
New cancer treatments have increased the life expectancy of children and adolescents, however, they are associated with excess weight and consequently with cardiovascular risk. The objective of this study was to relate dietary intake, cancer remission time with anthropometric indices related to cardiovascular risk in children and adolescents after cancer treatment. A cross-sectional study was carried out with children and adolescents, both sexes, monitored by AVOSOS in the city of Aracaju/SE. The volunteers were evaluated regarding clinical and anthropometric aspects (weight, height, waist circumference [WC], body mass index and waist/height ratio) and food consumption using a 24-hour recall. Pearson or Spearman correlation tests were applied, with p<0.05 being significant. 24 individuals were evaluated (45.8% children and 54.2% adolescents), mean age of 11.6 ± 0.84 years and disease remission time of 26.2 months. The types of cancers reported were leukemia, head and neck, lymphoma and other types (33.3%, 25.0%, 25.0% and 16.7%, respectively). Excess weight/obesity, abdominal fat and increased risk for cardiovascular disease were observed in 62.5%, 41.7% and 58.3% of the sample. The majority of participants had insufficient intake of fiber (95.8%), calcium (91.7%), iron (66.7%) and potassium (100%). A positive correlation was observed between WC and calories consumed (r=0.411, p=0.046) and dietary iron (r=0.407, p=0.049). The other variables analyzed were not correlated. Children and adolescents who survive cancer have an increased cardiovascular risk and a positive correlation between WC and caloric intake and dietary iron.
Downloads
References
Cancer facts and figures 2020 [Internet]. [cited 2023 Oct 17]. Available from: https://www.cancer.org/content/dam/cancer org/research/cancer-facts-and-statistics/annual-cancer-facts-and-figures/2020/cancer-facts-and-figures-2020.pdf
Gebauer J, Higham C, Langer T, Denzer C, Brabant G. Long-Term Endocrine and Metabolic Consequences of Cancer Treatment: A Systematic Review. Endocr Rev. 2019;40(3):711–67. DOI: 10.1210/er.2018-00092
York JM. Generously supported by with special appreciation to Long-Term Follow-Up Guidelines for Survivors of Childhood, Adolescent, and Young Adult Cancers [Internet]. 2018. Available from: www.survivorshipguidelines.org
Zhang FF, Kelly MJ, Saltzman E, Must A, Roberts SB, Parsons SK. Obesity in pediatric ALL survivors: a meta-analysis. Pediatrics. 2014;133(3):704-15. doi: 10.1542/peds.2013-3332.
Brasil. Ministério da Saúde. Secretaria de Atenção à Saúde. Departamento de Atenção Básica. Orientações para a coleta e análise de dados antropométricos em serviços de saúde: Norma Técnica do Sistema de Vigilância Alimentar e Nutricional - SISVAN / Ministério da Saúde, Secretaria de Atenção à Saúde, Departamento de Atenção Básica. Ministério da Saúde. 2011. 76 p.
World Health Organization. WHO child growth standards: length/height-for-age, weight-for-age, weight-for-length, weight for-height and body mass index-for-age: methods and development [Internet]. [cited 2023 Oct 17]. Available from: https:// www.who.int/publications/i/item/924154693X
Maffeis C, Banzato C, Talamini G. Waist-to-Height Ratio, a Useful Index to Identify High Metabolic Risk in Overweight Children. J Pediatr. 2008;152(2):207-213.e2. DOI: 10.1016/j.jpeds.2007.09.021
Ashwell M, Hsieh SD. Six reasons why the waist-to-height ratio is a rapid and effective global indicator for health risks of obesity and how its use could simplify the international public health message on obesity. Int J Food Sci Nutr. 2005;56(5):303– 7. DOI: 10.1080/09637480500195066
Freedman DS, Serdula MK, Srinivasan SR, Berenson GS. Relation of circumferences and skinfold thicknesses to lipid and insulin concentrations in children and adolescents: the Bogalusa Heart Study. Am J Clin Nutr. 1999;69(2):308–17. DOI: 10.1093/ajcn/69.2.308
Insitute of Medicine. 2006. Dietary Reference Intakes: The Essential Guide to Nutrient Requirements. Washington, DC: The National Academies Press. https://doi.org/10.17226/11537.
Institute of Medicine. 2005. Food and Nutrition Board. Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids (Macronutrients). National Academy Press.
Institute of Medicine (US) Committee to Review Dietary Reference Intakes for Vitamin D and Calcium; Ross AC, Taylor CL, Yaktine AL, et al., editors. Washington (DC): National Academies; 2011. https://doi.org/10.17226/13050
National Academies of Sciences, Engineering, and Medicine. 2019. Dietary Reference Intakes for Sodium and Potassium. Washington, DC: The National Academies Press. https://doi.org/10.17226/14.
Cohen J. Statistical Power Analysis for the Behavioral Sciences [Internet]. Routledge; 2013. Available from: https://www. taylorfrancis.com/books/9781134742707
Steliarova-Foucher E, Colombet M, Ries LAG, Moreno F, Dolya A, Bray F, Hesseling P, Shin HY, Stiller CA; IICC-3 contributors. International incidence of childhood cancer, 2001-10: a population-based registry study. Lancet Oncol. 2017: 18(6):719-731. doi: 10.1016/S1470-2045(17)30186-9.
Murphy-Alford AJ, White M, Lockwood L, Hallahan A, Davies PSW. Body composition, dietary intake and physical activity of young survivors of childhood cancer. Clinical Nutrition. 2019;38(2):842–7. DOI: 10.1016/j.clnu.2018.02.020
Veringa SJE, van Dulmen‐den Broeder E, Kaspers GJL, Veening MA. Blood pressure and body composition in long‐term survivors of childhood acute lymphoblastic leukemia. Pediatr Blood Cancer. 2012;58(2):278–82. DOI: 10.1002/pbc.23251
Chow EJ, Pihoker C, Hunt K, Wilkinson K, Friedman DL. Obesity and hypertension among children after treatment for acute lymphoblastic leukemia. Cancer. 2007;110(10):2313–20. DOI: 10.1002/cncr.23050
Delzenne NM, Olivares M, Neyrinck AM, Beaumont M, Kjølbæk L, Larsen TM, et al. Nutritional interest of dietary fiber and prebiotics in obesity: Lessons from the MyNewGut consortium. Clinical Nutrition. 2020;39(2):414–24. DOI: 10.1016/j. clnu.2019.03.002
Liberali R, Kupek E, Assis MAA De. Dietary Patterns and Childhood Obesity Risk: A Systematic Review. Childhood Obesity. 2020;16(2):70–85. DOI: 10.1089/chi.2019.0059
Zhang J, Wang H, Wang Y, Xue H, Wang Z, Du W, et al. Dietary patterns and their associations with childhood obesity in China. British Journal of Nutrition. 2015;113(12):1978–84. DOI: 10.1038/ejcn.2015.8
Hilton C, Sabaratnam R, Drakesmith H, Karpe F. Iron, glucose and fat metabolism and obesity: an intertwined relationship. Int J Obes (Lond). 2023;47(7):554-563. doi: 10.1038/s41366-023-01299-0.
Alshwaiyat NM, Ahmad A, Wan Hassan WMR, Al-Jamal HAN. Association between obesity and iron deficiency (Review). Exp Ther Med. 2021;22(5):1268. doi: 10.3892/etm.2021.10703.
Panichsillaphakit E, Suteerojntrakool O, Pancharoen C, Nuchprayoon I, Chomtho S. The Association between Hepcidin and Iron Status in Children and Adolescents with Obesity. J Nutr Metab. 2021; 2021:9944035.
Suárez-Ortegón MF, Prats-Puig A, Bassols J, Carreras-Badosa G, McLachlan S, Wild SH, López-Bermejo A, Fernández Real JM. Iron status and cardiometabolic risk in children. Diabetes Res Clin Pract. 2023;202:110795. doi: 10.1016/j. diabres.2023.110795.
Nunes MMA, Figueiro JN, Alves JGB. Excesso de peso, atividade física e hábitos alimentares entre adolescentes de diferentes classes econômicas em Campina Grande (PB). Rev Assoc Med Bras. 2007;53(2). DOI: 10.1590/S0104-42302007000200017
Kuperman H, Battistin C, Moreira ACF, Cornacchioni AL, Odone Filho V, Setian N, et al. Avaliação dos principais efeitos endócrinos tardios em crianças e adolescentes sobreviventes ao tratamento de neoplasias malignas. Arq Bras Endocrinol Metabol. 2010;54(9):819–25. DOI: 10.1590/S0004-27302010000900008
Oliveira BA de, Lins MM, Pedrosa F, Cabral PC, Barbosa JM. Estado nutricional de crianças e adolescentes sobreviventes de leucemia linfoide aguda tratados em um Centro de Referência da Região Nordeste do Brasil. Revista de Nutrição. 2013;26(3):271–81. DOI: 10.1590/S1415-52732013000300002
Couto-Silva AC, Brauner R, Adan LF. Seqüelas endócrinas da radioterapia no tratamento do câncer na infância e adolescência. Arq Bras Endocrinol Metabol. 2005;49(5):825–32. DOI: 10.1590/S0004-27302005000500025
Chiara VL, Silva HGV da, Barros ME, Rêgo AL, Ferreira AL, Pitasi BA, et al. Correlação e concordância entre indicadores de obesidade central e índice de massa corporal em adolescentes. Revista Brasileira de Epidemiologia. 2009;12(3):368–77.
Zhang FF, Kelly MJ, Saltzman E, Must A, Roberts SB, Parsons SK. Obesity in Pediatric ALL Survivors: A Meta-Analysis. Pediatrics. 2014;133(3):e704–15. DOI: 10.1542/peds.2013-3332
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 O Mundo da Saúde
This work is licensed under a Creative Commons Attribution 4.0 International License.
