Study on the practice of self-medication in adults from Paraná during the COVID-19 pandemic
DOI:
https://doi.org/10.15343/0104-7809.202347e12992022PKeywords:
Self-medication, COVID-19, Medicine, SARS-CoV-2Abstract
The lack of knowledge about medications to prevent or treat COVID-19, as well as the use of previous prescriptions and the storage of medicines at home, can encourage self-medication. Thus, this work aimed to study the practice of self[1]medication in adult individuals from Paraná during the COVID-19 pandemic. Therefore, a quantitative-descriptive and cross-sectional study was carried out with the online distribution of questionnaires reaching people from Paraná aged ≥18 years old. The results show that participants (n=329) between 18-37 years old were the most frequent responders. Approximately 24% self-medicated, influenced mainly by having the medication at home (21%) or by family members or friends (13%). Self-medication with vitamins (28%) and ivermectin (20%) in preventing COVID-19 was frequent. However, over-the-counter drugs used for respiratory symptoms were mostly analgesics/antipyretics (17%) and muscle relaxants (10%). Additionally, participants who tested positive for COVID-19 self-medicated with vitamins (6%), ivermectin or nitazoxanide (4%), and analgesics/antipyretics (3%). The use of ivermectin or nitazoxanide for COVID-19 has not been scientifically proven for this purpose. Finally, self-medication for non-respiratory symptoms was higher for analgesics and antipyretics (14%), muscle relaxants (9%), and laxatives (9%). Although little used, self-medication with chloroquine/ hydroxychloroquine was cited, even without an efficacy study for COVID-19. It is concluded that more than half of the adult participants from Paraná self-medicated during the COVID-19 pandemic, with the most frequent drug classes being analgesics/antipyretics, muscle relaxants, laxatives, vitamins, and ivermectin.
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References
Montastruc J-L, Bondon-Guitton E, Abadie D, et al. Pharmacovigilance, risks and adverse effects of self-medication. Therapies. 2016; 71: 257–262. Diponível em: http://dx.doi.org/10.1016/j.therap.2016.02.012.
Quincho-Lopez A, Benites-Ibarra CA, Hilario-Gomez MM, et al. Self-medication practices to prevent or manage COVID-19: A systematic review. PLoS One. 2021; 16: 1–12. Disponível em: https://doi.org/10.1371/journal.pone.0259317.
Yáñez JA, Chung SA, Román BR, et al. Prescription, over-the-counter (OTC), herbal, and other treatments and preventive uses for COVID-19. Environmental Managemento of COVID-19. 2021. Cap. 14. ISBN 978-0-323-85780-2. Disponível em: https://doi. org/10.1016/B978-0-323-85780-2.00001-9.
Onchonga D. A Google Trends study on the interest in self-medication during the 2019 novel coronavirus (COVID-19) disease pandemic. Saudi Pharm J. 2020; 28: 903–904. Disponível em: https://doi.org/10.1016/j.jsps.2020.08.003.
Lei X, Jiang H, Liu C, et al. Self-medication practice and associated factors among residents in Wuhan, China. Int J Environ Res Public Health. 2018; 15(68):1-10. Disponível em: http://doi.org/10.3390/ijerph15010068.
Makowska M, Boguszewski R, Nowakowski M. Self-Medication-Related Behaviors and Poland’s. Int J Env Res Salud Pública. 2020; 17, 8344. Disponível em: http://doi.org/10.3390/ijerph17228344.
García-Albéniz X, Amo J, Polo R, et al. Systematic review and meta-analysis of randomized trials of hydroxychloroquine for the prevention of COVID-19. Eur J Epidemiol. 2022; 37: 789–796. Disponível em: https://doi.org/10.1007/s10654-022-00891-4.
Cheng Q, Zhao G, Chen J, Jia Q, Fang Z. Comparative efficacy and safety of pharmacological interventions for severe COVID- 19 patients. Medicine. 2022; 101:41 Disponível em: http://doi.org/10.1097/MD.0000000000030998.
Ylä-Rautio H, Siissalo S, Leikola S. Drug-related problems and pharmacy interventions in non-prescription medication, with a focus on high-risk over-the-counter medications. Int J Clin Pharm 2020; 42: 786–795. Disponível em: https://doi.org/10.1007/s11096-020- 00984-8.
Baracaldo-Santamaría D, Pabón-Londoño S, Rojas-Rodriguez LC. Drug safety of frequently used drugs and substances for selfmedication in COVID-19. Ther Adv Drug Saf. 2022; 13: 1–14. Disponível em: https://doi.org/10.1177/20420986221094141.
Rabelo Melo JR, Duarte EC, Moraes MV, et al. Self-medication and indiscriminate use of medicines during the COVID-19 pandemic. Cad Saude Publica. 2021; 37: 0–4. Disponível em: http://doi.org/10.1590/0102-311X00053221.
Mota IA, Oliveira-Sobrinho GD, Morais LPS, et al. Impact of COVID-19 on eating habits, physical activity and sleep in Brazilian healthcare professionals. Arq Neuropsiquiatr. 2021; 79: 429–436. Disponível em: https://doi.org/10.1590/0004-282X-ANP-2020-0482.
Alonso-Castro AJ, Ruiz-padilla AJ, Ortiz-cortes M, et al. Self-treatment and adverse reactions with herbal products for treating symptoms associated with anxiety and depression in adults from the central-western region of Mexico during the Covid-19 pandemic. J Ethnopharmacol. 2021; 23;272:113952. Disponível em: https://doi.org/10.1016/j.jep.2021.113952.
Goldlin ATJ; Prakash M. Cyberchondria and its Impact on Self-Medication and Self Care in Covid-19 Pandemic - A Cross Sectional StudyNo Title. Biomed Pharmacol J. 2021; 14: 2235–2244. Disponível em: https://dx.doi.org/10.13005/bpj/2322.
Gaviria-Mendoza A, Mejía-Mazo DA, Duarte-Blandón C, et al. Self-medication and the ‘infodemic’ during mandatory preventive isolation due to the COVID-19 pandemic. Ther Adv Drug Saf. 2022; 13: 1–12. Disponível em: https://doi.org/10.1177/20420986211072376.
Albarrán KF, Zapata LV. Analysis and quantification of self-medication patterns of customers in community pharmacies in southern Chile. Pharm World Sci. 2008; 30: 863–868. Disponível em: https://doi.org/10.1007/s11096-008-9241-4.
Barakat A, Mohasseb M. Self-Medication with Antibiotics Based on the Theory of Planned Behavior among an Egyptian Rural Population during the Era of COVID-19 Pandemic. Egypt J Community Med. 2023;40(1): 51-60. Disponível em: https://doi. org/10.21608/ejcm.2022.139501.1220.
Acharya A, Shrestha MV, Karki D. Self-medication among Medical Students and Staffs of a Tertiary Care Centre during COVID-19 Pandemic: A Descriptive Cross-sectional Study. J Nepal Med Assoc. 2022; 60: 59–62. Disponível em: https://doi.org/10.31729/ jnma.7247.
Alexander J, Tinkov A, Tor AS, et al. Early Nutritional Interventions with Zinc , Selenium Against Progressive COVID-19. Nutrients. 2020; 12: 1–12. Disponível em: https://doi.org/10.3390/nu12082358.
Mercola J, Grant WB, Wagner CL. Evidence regarding vitamin d and risk of covid-19 and its severity. Nutrients. 2020; 12: 1–24. Disponível em: https://doi.org/10.3390/nu12113361.
Ruiz-Padilla AJ, Alonso-Castro AJ, Preciado-Puga M, et al. Use of allopathic and complementary medicine for preventing SARSCoV-2 infection in Mexican adults: A national survey. Saudi Pharm J. 2021; 29: 1056–1060. Disponível em: https://doi.org/10.1016/j. jsps.2021.07.009.
Ruiz-Padilla AJ, Alonso-Castro AJ, Preciado-Puga M, et al. Use of allopathic and complementary medicine for preventing SARSCoV-2 infection in Mexican adults: A national survey. Saudi Pharm J. 2021; 29: 1056–1060. Disponível em: https://doi.org/10.1016/j. jsps.2021.07.009.
Amuzie CI, Kalu KU, Izuka M, et al. Prevalence, pattern and predictors of self-medication for COVID-19 among residents in Umuahia, Abia State, Southeast Nigeria: policy and public health implications. J Pharm Policy Pract. 2022; 15: 1–9. Disponível em: https://doi.org/10.1186/s40545-022-00429-9.
Okoye OC, Adejumo OA, Opadeyi AO, et al. Self medication practices and its determinants in health care professionals during the coronavirus disease-2019 pandemic: cross-sectional study. Int J Clin Pharm. 2022; 44: 507–516. Disponível em: https://doi. org/10.1007/s11096-021-01374-4.
Formiga FR, Leblanc R, Rebouças JS, et al. Ivermectin : an award-winning drug with expected antiviral activity against. J Control Release. 2021; 10;329:758-761. Disponível em: https://doi.org/10.1016/j.jconrel.2020.10.009
Saleem RT, Butt MH, Ahmad A, Amin M, Amir AAA et al. Practices and Attitude of Self-medication during COVID-19 Pandemic in University Students with Interventional Role of Pharmacist: a Regional Analysis. Lat Am J Pharmacy. 2021; 40: 1946–53.
Vasquez-Elera LE, Failoc-Rojas VE, Martinez-Rivera RN, et al. Self-medication in hospitalized patients with COVID-19: A crosssection study in northern Peru. Germs. 2022; 12: 46–53. Disponível em: https://doi.org/10.18683/germs.2022.1305.
Heshmatifar N, Quchan ADM, Tabrizi ZM, et al. Prevalence and Factors Related to Self-Medication for COVID-19 Prevention in the Elderly. Iran J Ageing. 2021; 16: 112–127. Disponível em: https://doi.org/10.32598/sija.16.1.2983.1.
Kournoutou GG, Dinos G. Azithromycin through the Lens of the COVID-19 Treatment. Antibiotics. 2022; 11: 1063. Disponível em: https://doi.org/10.3390/antibiotics11081063.
Tobaiqi MA, Mahrous KW, Batoot AM, et al. Prevalence and association of self-medication on patient health in Medina. Med Sci. 2021; 25: 2685–2697.
Shrestha AB, Aryal M, Magar JR, et al. The scenario of self-medication practices during the covid-19 pandemic; a systematic review. Ann Med Surg. 2022; 82: 104482. Disponível em: https://doi.org/10.1016/j.amsu.2022.104482.
Zhang A, Hobman EV, Barro P, et al. Self-medication with antibiotics for protection against COVID-19: The role of psychological distress, knowledge of, and experiences with antibiotics. Antibiotics. 2021; 10: 1–14. Disponível em: https://doi.org/10.3390/ antibiotics10030232.
Heydargoy MH. The Effect of the Prevalence of Covid-19 on Arbitrary Use of Antibiotics. Iran J Med Microbiol. 2020; 14(4): 374- 378. Disponível em: http://doi.org/10.30699/ijmm.14.4.374
Choudhary N, Lahiri K, Singh M. Increase and consequences of self-medication in dermatology during COVID-19 pandemic: An initial observation. Dermatol Ther. 2021; 34: 2–4. Disponível em: http://doi.org/10.1111/dth.14696.
Zhang C, Jin H, Wen YF, et al. Efficacy of COVID-19 Treatments: A Bayesian Network Meta-Analysis of Randomized Controlled Trials. Front Public Heal. 2021; 9: 1–18. Disponível em: http://doi.org/10.3389/fpubh.2021.729559.
Langford BJ, Soucy JR, Leung V, et al. Antibiotic resistance associated with the covid-19 pandemic: a systematic review and metaanalysis. Clin Microbiol Infect. 2023; 29: 302–309.
Sikdar KMYK, Anjum J, Bahar NB, et al. Evaluation of sleep quality, psychological states and subsequent self-medication practice among the Bangladeshi population during Covid-19 pandemic. Clin Epidemiol Glob Heal. 2021; 12: 100836. Disponível em: https:// doi.org/10.1016/j.cegh.2021.100836
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